≥99.0

Overall, the use of TiO2 in factory settings plays a crucial role in enhancing the quality, performance, and appearance of a wide range of products. Its unique properties make it an invaluable ingredient in various industrial processes, allowing manufacturers to create high-quality, durable, and visually appealing finishes. As technology continues to advance, the demand for TiO2 is expected to grow, further solidifying its importance in the manufacturing industry.

All samples (n = 6) were irradiated in a 96 well plate using an LED panel on top for 3 and 6 h before analysis. An identical set of samples were kept in the dark as controls. The temperature was checked and did not go over 37 °C. The intensity of light was also measured and was constant at 19,500.10 lux. (43.33 W in 0.2 m²), about 5 times less than actual solar light intensity on Earth's surface Therefore, these findings are indicative of even greater danger in real life.

In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”

Reason for listing: CNNC Huayuan Titanium Dioxide Co., Ltd., a well-known brand of titanium dioxide factory, started in 1989, specializing in the research and development, production, sales and service of titanium dioxide products. One of the titanium dioxide enterprises producing more than 10,000 tons.

Our scientific experts applied for the first time the 2018 EFSA Scientific Committee Guidance on Nanotechnology to the safety assessment of food additives. Titanium dioxide E 171 contains at most 50% of particles in the nano range (i.e. less than 100 nanometres) to which consumers may be exposed.  

There are many uses of titanium dioxide that we don't know about because they were made exempt from being on the package in 1977, said Faber, who added that nothing much has changed since – other than the FDA approving some other uses of the color additive, such as expanding the use of mica-based pearlescent pigments (prepared from titanium dioxide) as color additives in distilled spirits over recent years.

Hebei Caiqing Material Technology Co., Ltd. was established in 2005 and has been at the forefront of chemical product research and development. Focusing on the field of titanium dioxide, the company has played a vital role in meeting global demand, providing personalized customization services to global customers. With the continuous expansion of the titanium dioxide market, Hebei Caiqing Material Technology Co., Ltd. is ready to meet the industry's growing demand in terms of production and service.

As a widely used substance with multiple applications, research is being carried out to improve the production process to reduce the levels of chemicals used and waste produced, and to recycle any by-products.

According to the feedback of the manufacturers, the new mainstream factory has risen, and the overall transaction center of the market has moved up. On the demand side, the terminal is currently considering stocking up in autumn, and the actual transaction willingness is enhanced; From the supply side, some mainstream manufacturers have increased the load, and the actual output of the industry has increased. Some plastics and papermaking related downstream feedback some of the tight models are more expensive. Recent titanium dioxide raw material price trend is strong, titanium dioxide price upward support also increased, comprehensive market factors, the current price of titanium dioxide rose again.

Inflammation of the intestines

Genotoxicity and cytotoxicity 

States looking to ban titanium dioxide as a food additive