The Scientific Facts

In addition to its aesthetic benefits, lithopone also offers practical advantages for leather suppliers. Due to its low cost and wide availability, lithopone is a cost-effective option for leather manufacturers looking to minimize production expenses without compromising on quality. Its stable chemical properties also make it easy to work with during the manufacturing process, resulting in a smooth and efficient production line.

From studies deemed relevant, the experts found that titanium dioxide as a food additive is poorly absorbed by the gastrointestinal tract of mice and rats, with no adverse effects observed in short-term studies in rodents receiving titanium dioxide in their diets. No observed adverse effect levels (NOAELs) of 15,000 milligrams per kilogram of bodyweight (mg/kg BW) per day and 5,000 mg/kg BW per day—the highest doses tested—were established for mice and rats, respectively.

In general, nanoparticles have been shown to accumulate in the body, particularly in organs in the gastrointestinal tract, along with the liver, spleen, and capillaries of the lungs.

Fig. 4. Hemolysis (%) values of samples, A: 0.2 mg/mL P25TiO₂NPs; B: 0.02 mg/mL P25TiO₂NPs; C: 0.2 mg/mL VitaminB2@P25TiO₂NPs; D: 0.02 mg/mL VitaminB2@P25TiO₂NPs after 3 h of irradiation (red) and 6 h (blue). SD <5 for all samples and p <0.05 between C-D and A-B.

As early as sixty years ago, zinc sulphide was first thought of as a pigment for coloring India rubber and a patent for the process of its manufacture was issued in England. But it was not until twenty years later that zinc sulphide and its manufacture was seriously considered as a pigment for paint, and in 1874 a patent was issued for a process of manufacturing a white pigment, composed of zinc sulphide and barium sulphate, known as Charlton white, also as Orr's white enamel. This was followed in 1876 by a patent issued to a manufacturer named Griffith and the product, which was similar in character to Charlton white, was known as Griffith's patent zinc white. In 1879 another patent for a more novel process was obtained by Griffith & Cawley, the product made under this process proving the best of the series placed upon the market up to that date. After that time many new processes were patented, all, however, tending to the same object, that of producing a white pigment, composed of zinc sulphide and barium carbonate, the results, however, in many cases ending with failure.

The EU expert panel did not identify an immediate health concern linked to TiO₂ when used as a food additive. However, due mainly to uncertainties concerning the safety of TiO₂ nanoparticles, the panel concluded that TiO₂ as a food additive (E171) could no longer be considered safe.

Lyophilized vitamins@P25TiO₂NPs were obtained through the described methods with excellent reproducibility and yield: over 99% of initial P25TiO₂NPs were functionalized.

Although the evidence for general toxic effects was not conclusive, on the basis of the new data and strengthened methods we could not rule out a concern for genotoxicity and consequently we could not establish a safe level for daily intake of the food additive, commented Matthew Wright, member of the EFSA's Food Additives and Flavourings Panel in a press statement.

3. Photocatalysis The photocatalytic properties of anatase make it valuable for environmental applications such as air and water purification. Manufacturers are exploring its potential in self-cleaning surfaces and photocatalytic reactors, which can degrade pollutants under UV light.

The alarming fact of this study is that it was only conducted for 100 days, I have been wearing makeup daily for at least the last fifteen years & would have eaten kilo's of lipstick in my life time - what effects has this had on my system & health??

Reacting to the report, France’s ministers of health, agriculture and economy instructed the country’s food health and safety agency, Anses, to investigate whether the additive poses a risk for human health.

The study was said to be prompted by “growing concerns that daily oral… Intake is associated with an increased risk of chronic intestinal inflammation and carcinogenesis”, or cancer formation”.